id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017008-c7skxte0	Méthot, Pierre-Olivier	Emerging Disease and the Evolution of Virulence: The Case of the 1918–1919 Influenza Pandemic	2014-08-22		.txt	text/plain	17589	788	49	Next, we describe the biology of infl uenza viruses with a focus on the 1918-19 pandemics and we move on to the ecological-evolutionary explanations of its exceptional virulence, paying attention to the trade-off model, before turning to molecular 4 On the history, epistemology, and social aspects of the concept of emerging disease see Grmek ( 1993 ); Farmer ( 1996 ) , King ( 2004 ) ; and Weir and Mykhalovski ( 2010 ) . 6 Whereas the ecological (or exogenous) style focuses on processes (e.g. selective pressures, population density, within and between host competition, and so on) acting on the hosts and the pathogen, the molecular (or endogenous) style traces the evolutionary pathway, or patterns, of the infl uenza virus from animal(s) to man, and, by constructing molecular phylogenies, identifi es particular genes for pathogenesis and mutation sites within lineages.	./cache/cord-017008-c7skxte0.txt	./txt/cord-017008-c7skxte0.txt