id author title date pages extension mime words sentences flesch summary cache txt cord-017527-ylng1us2 Herman, Philippe Biosafety Recommendations on the Handling of Animal Cell Cultures 2014-11-05 .txt text/plain 10237 453 38 While biosafety recommendations (as outlined hereafter) are principally aimed at providing maximal protection of human health (including laboratory workers) and the environment, it is recognised that many of the precautionary measures will also directly benefit the quality of research activities involving animal cell cultures. The methodology of biological risk assessment of contained use activities involving pathogenic and/or genetically modified organisms (GMO) identifies and takes into account the probability of occurrence and the severity of a potential negative effect on public health (including the exposed workers) and/or the environment. The risk assessment applied to animal cell cultures relies on a thorough evaluation of both the intrinsic properties of the cell culture -including subsequent properties acquired as a result of genetic modification(s) -and the possibility that the cell culture may inadvertently be contaminated or deliberately infected with pathogenic micro-organisms. ./cache/cord-017527-ylng1us2.txt ./txt/cord-017527-ylng1us2.txt