id author title date pages extension mime words sentences flesch summary cache txt cord-023564-kpqvyxxe nan Viral gastroenteritis: Causes, pathophysiology, immunology, treatment, and epidemiology 2004-09-14 .txt text/plain 2512 145 45 This chapter discusses the causes, pathophysiology, immunology, treatment, and epidemiology of viral gastroenteritis. Infection with gastroenteritis agents can be asymptomatic or can be followed by mild or severe disease, including vomiting or diarrhea or both, and can be fatal because of severe dehydration. Infection with gastroenteritis agents can be asymptomatic, or be followed by mild or severe disease including vomiting or diarrhoea or both, and can be fatal as a consequence of severe dehydration. The main diarrhoeogenic agents comprise four virus families: rotaviruses, enteric adenoviruses, human caliciviruses (Norwalk-and Sapporo-like viruses, now termed noro-and sapoviruses) and astroviruses, and cause diarrhoea at frequencies of 20-30%, 5%, 5-10%, and 5%, respectively. By contrast, epidemic disease is found in all ages, mainly caused by Norwalk-and Sapporo-like viruses (human caliciviruses), rotaviruses of group B (in China), and sometimes astroviruses. Systemic and intestinal antibody secreting cell responses and correlates of protective immunity to human rotaviruses in a gnotobiotic pigs model of disease ./cache/cord-023564-kpqvyxxe.txt ./txt/cord-023564-kpqvyxxe.txt