id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-026340-2nf97zvc	Singh, Ranjana	Chloroquine: A Potential Drug in the COVID-19 Scenario	2020-06-07		.txt	text/plain	7542	412	55	In this review article, we have systematically searched for details of COVID-19 pandemic till May 2020 and assembled few data pertaining to (i) Corona viruses; (ii) SARS-CoV2, the virus that causes COVID-19' and (iii) How chloroquine and hydroxychloroquine mediates anti-viral effect in both prophylactic and therapeutic setting. The Corona Study Group (CSG) of the International Committee on Taxonomy of Viruses (ICTV) after assessing the etiological agent named it SARS-CoV2 (Severe Acute Respiratory Syndrome Corona Virus2) and the disease outbreak as COVID-19 (Corona Virus Disease-Year of Identification). During COVID-19, SARS-CoV2 S-protein binds to host cell's receptor ACE2 (Belouzard et al. As for the case of SARS-CoV, it was shown that the binding specificity of virus to host cell was due to 3 prime amino acid residues in S1 protein at positions 360, 479, and 487.	./cache/cord-026340-2nf97zvc.txt	./txt/cord-026340-2nf97zvc.txt