id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-076082-4kpkhz0o	Lam, Tommy Tsan-Yuk	Evolutionary and Transmission Dynamics of Reassortant H5N1 Influenza Virus in Indonesia	2008-08-22		.txt	text/plain	6973	312	44	The H5N1 highly pathogenic avian influenza (HPAI) virus was originally isolated from a farmed goose in Guangdong province of China in 1996 [1] , and soon spread to live-poultry markets in Hong Kong [2] , resulting in 18 cases of human infection in 1997, 6 of which were fatal [3, 4] . We found previously unrecognized phylogenetic discordance between gene trees involving human and cat isolates (n = 25, denoted in red in Figures 1, S1-S3)-the main focus of our study-suggesting that they are reassortant viruses descending from group 2 and 3 lineages. To further investigate the putative reassortant human and cat viruses, a selected dataset (n = 24) of manually concatenated full genomes (Figure 2A ; see Methods) of Indonesian H5N1 HPAI viruses were analyzed using more sophisticated analysis methods, including similarity plots, bootscan analyses and GARD analyses (genetic algorithm for recombination detection).	./cache/cord-076082-4kpkhz0o.txt	./txt/cord-076082-4kpkhz0o.txt