id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-104286-5yw4zwo4	Doane, F. W.	Virus morphology as an aid for rapid diagnosis.	1980		.txt	text/plain	2206	138	39	A specimen is inoculated into a host system (tissue culture, eggs, animals), and subsequent detection and identification of an isolated virus depends on indicators such as cytopathic effect, hemagglutinin, complement fixation, etc. The following brief review will examine some of the ways in which virus morphology can serve as an important aid for rapid virus diagnosis, some of the limitations of this approach, and current and future developments in electron microscopy relating to diagnostic virology. The same results can be obtained within one hour if one uses immunoelectron microscopy (IEM), by which the virusantiserum mixtures are negatively stained and examined on an EM specimen grid. A major advantage of using electron microscopy for rapid virus diagnosis is that one can actually see the virus and identify it by its morphology. Hepatitis A: detection by immune electron microscopy of a virus-like antigen associated with acute illness	./cache/cord-104286-5yw4zwo4.txt	./txt/cord-104286-5yw4zwo4.txt