id author title date pages extension mime words sentences flesch summary cache txt cord-253594-9gbo8viu Konieczny, Leszek The COVID-19 Puzzle 2020-05-31 .txt text/plain 1366 90 49 From the epidemiological perspective, an important factor affecting the spread of the virus is the proximity between infection targets. The bacterial genome includes a repository of viral genetic sequences -effectively a "catalogue" of known viruses. Its effects appear to depend on the carrier's age: many people, particularly young ones, remain asymptomatic, while older individuals frequently develop serious -even life-threateningsymptoms. Variable susceptibility to infection may be a consequence of the general state of health, which, of course, depends on the individual's age and co-morbidities -particularly metabolic ones (e.g. diabetes). Since the virus preferentially attacks the lungs, we can point to tobacco smoking as a factor, which promotes infection by damaging lung tissue. One mechanism which exhibits clear susceptibility to external disruption (including the presence of unusual substances) is protein folding. Genetic polymorphism undoubtedly results in individual variability, including well-known differences in alcohol tolerance. ./cache/cord-253594-9gbo8viu.txt ./txt/cord-253594-9gbo8viu.txt