id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-254527-zddwajzg	Junter, Guy-Alain	Polysaccharide-based chromatographic adsorbents for virus purification and viral clearance	2020-01-13		.txt	text/plain	16940	907	42	Table 2 gathers a variety of packed-bed column chromatography procedures applied to viral particle purification in which the stationary phase consists of AG -essentially Sepharose® ("Separation-Pharmacia-AG"; GE Healthcare, Chicago, Ill.) (Seph) -or CELe.g., Cellufine™ (JNC Corporation, Tokyo, Japan) -gel beads, modified to fulfill varying separation modes, i.e., ion exchange, size exclusion and affinity (Table 3 [77] [78] [79] [80] [81] ). For instance, the purification process for Nuwiq®, a recombinant coagulation factor VIII (a blood-clotting protein whose deficiency is associated with hemophilia A) patented by Octapharma AG (Lachen, Switzerland) [195] , includes solvent/detergent (S/D) treatment, Planova NF, and five chromatography steps using PS-based stationary phases, i.e., MMC (Capto MMC), CEC (SP Seph FF), AFC (VIIISelect, a Capto matrix with factor VIIIselective ligand), AEC (Q Seph FF) and SEC (Superdex 200).	./cache/cord-254527-zddwajzg.txt	./txt/cord-254527-zddwajzg.txt