id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-255690-xc4bxin4	Rolain, Jean-Marc	Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century	2007-07-16		.txt	text/plain	7020	351	39	Here we review available in vitro and in vivo data on the effects of CQ/HCQ on bacterial, fungal and viral infections, with the concept that manipulation of the intracellular pH in cells and modification of glycosylation of proteins by lysosomotropic agents instead of antimicrobial compounds is a powerful approach as new therapeutic strategies for the prevention and therapeutic management of several infectious diseases, including some of great public health concern worldwide. Coxiella burnetii [5, 13] Histoplasma capsulatum [24] HIV [2, [29] [30] [31] [32] ] Tropheryma whipplei [7, 8] Cryptococcus neoformans [15, 25] SARS-CoV [33, 34] Legionella pneumophila [11] Paracoccidioides brasiliensis [26] Influenza viruses [35] [36] [37] [38] Francisella tularensis [12] Penicillium marneffei [15, 27] Flavivirus, including yellow fever virus [39] Mycobacterium tuberculosis [14] Aspergillus fumigatus [28] Rubella virus [ tetracycline and quinolone regimen for at least 4 years, with a high percentage of relapses [6] .	./cache/cord-255690-xc4bxin4.txt	./txt/cord-255690-xc4bxin4.txt