id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-259927-xh9cw9ao	Papadopoulos, Nikolaos G.	Promising approaches for the treatment and prevention of viral respiratory illnesses	2017-07-21		.txt	text/plain	7342	400	34	When considering prevention or treatment of viral respiratory tract infections, potential targets include the causative pathogens themselves but also the immune response, disease transmission, or even just the symptoms. Here we provide an overview of the options and highlight some of the most promising approaches in vRTI treatment, including symptomatic medication, immunomodulatory drugs, antiviral agents, and natural products, as well as in vRTI prevention, ranging from vaccines to immunostimulators and public health policies. Early in vivo evidence suggested that azithromycin has anti-inflammatory and antiviral effects through induction of interferon-stimulated gene mRNA expression and reduced viral replication and release in patients with asthma and chronic obstructive lung disease. mAb therapies to viral infections, such as EBV (rituximab) or RSV (palivizumab), provide passive immunization and are licensed, whereas similar agents targeting influenza and other viruses are in preclinical development.	./cache/cord-259927-xh9cw9ao.txt	./txt/cord-259927-xh9cw9ao.txt