id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-260705-huyyw5z6	Moshe, Adi	Virus-Induced Aggregates in Infected Cells	2012-10-17		.txt	text/plain	5063	265	39	During infection, many viruses induce cellular remodeling, resulting in the formation of insoluble aggregates/inclusions, usually containing viral structural proteins. The aggregates are utilized by viruses to house a large complex of proteins of both viral and host origin to promote virus replication, translation, intraand intercellular transportation. In plant cells, both RNA and DNA viruses are associated with large inclusions detected in the cytoplasm and nucleus, however, their role in virus propagation or oppositely in virus restraint is less investigated than in infected mammalian cells. In general, mammalian and plant viruses make use of aggregates as scaffolds for anchoring the replication complex, increasing the local concentration of viral and host components required for replication and assembly, and shielding the process of replication from host defense.	./cache/cord-260705-huyyw5z6.txt	./txt/cord-260705-huyyw5z6.txt