id author title date pages extension mime words sentences flesch summary cache txt cord-262722-cz3ce29n Kuzmanovic, Deborah A. A novel application of small-angle scattering techniques: Quality assurance testing of virus quantification technology 2008-03-31 .txt text/plain 5479 271 50 Abstract Small-angle scattering (SAS) techniques, like small-angle X-ray scattering (SAXS) and small-angle neutron scattering (SANS), were used to measure and thus to validate the accuracy of a novel technology for virus sizing and concentration determination. Additionally, scattering methods such as classical light scattering, small-angle X-ray scattering (SAXS) and small-angle neutron scattering (SANS) have also been employed to measure the concentration of samples when the molecular weight of the virus is known (Guinier, 1939; Guinier and Fournet, 1955; Jacrot and Zaccai, 1981; Koch et al., 2003) . The primary goal of this study is to explore the utility of using small-angle scattering (SAS) techniques, such as SAXS and SANS, as a general approach to the evaluation and quality assurance testing of virus characterization technology, using the integrated virus detection system (IVDS) instrument as a test technology. Specifically, it was determined using SAXS and SANS that the virus sizing and concentration technology, IVDS, can accurately measure the size of synthetic latex microspheres. ./cache/cord-262722-cz3ce29n.txt ./txt/cord-262722-cz3ce29n.txt