id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266985-9qwttt2y	Gale, P.	Applications of omics approaches to the development of microbiological risk assessment using RNA virus dose–response models as a case study	2014-11-04		.txt	text/plain	8073	341	43	At present, the great strength of gene sequence data appears to be in giving information on the distribution and proportion of susceptible genotypes (for example due to the presence of the appropriate pathogen‐binding receptor) in the host population rather than in predicting specificities from the amino acid sequences concurrently obtained. The nature of the mutant spectrum in RNA viruses greatly complicates the application of omics approaches to the development of mechanistic dose–response models and prevents prediction of risks of disease progression (given infection has occurred) at the level of the individual host. The binding of NoV capsid protein to its HBGA receptor Table 1 Breakdown of the initial infection process into four steps for building a mechanistic dose-response relationship for RNA viruses through the oral route: information needs Host glycans play a central role in the pathogen infection process including binding of virus to specific receptors in steps 1 and 2 and also in the immune system.	./cache/cord-266985-9qwttt2y.txt	./txt/cord-266985-9qwttt2y.txt