id author title date pages extension mime words sentences flesch summary cache txt cord-270335-8vqi9c68 Seifert, Stephanie N Rousettus aegyptiacus Bats Do Not Support Productive Nipah Virus Replication 2019-11-04 .txt text/plain 3272 155 47 Nipah virus is capable of infecting a broad range of hosts including humans, pigs, ferrets, dogs, cats, hamsters, and at least 2 genera of bats. Studies of wild caught Pteropus spp suggest potential for viral recrudescence [16, 23] ; however, the hypothesis that NiV may persist in an individual bat and re-emerge under times of stress has yet to be confirmed experimentally. In contrast, the Egyptian fruit bat (EFB), Rousettus aegyptiacus, belongs to the same taxonomic family as Pteropus spp, Pteropodidae, and has been successfully used to model Marburg virus transmission [24, 25] and serological cross-reactivity after filovirus challenge [26] . Previous studies have demonstrated that EFB cells are permissive to Ebola virus, but experimentally challenged bats did not shed virus or support productive replication [38, 39] despite compatibility between the Ebola virus glycoprotein and the host receptor, NPC1 [40] . ./cache/cord-270335-8vqi9c68.txt ./txt/cord-270335-8vqi9c68.txt