id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-271091-ffn59sgf	Galao, Rui P	Saccharomyces cerevisiae: a versatile eukaryotic system in virology	2007-10-10		.txt	text/plain	6539	318	42	These include the analysis of the function of individual proteins from important pathogenic viruses, the elucidation of key processes in viral replication through the development of systems that allow the replication of higher eukayotic viruses in yeast, and the use of yeast in antiviral drug development and vaccine production. Although the expression of viral proteins in yeast not always necessarily reflects their role in higher eukaryotes, here we selected some examples in which the analysis in yeast of their effect on highly conserved cellular processes such as cell cycle control, apoptosis or mRNA degradation have contributed to the current understanding of the pathogenesis of important viral pathogens such as HIV-1 and HCV. The identification of the host factors involved in viral RNA replication is a priority area of research in virology because it can provide new targets for antiviral drug development.	./cache/cord-271091-ffn59sgf.txt	./txt/cord-271091-ffn59sgf.txt