id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-271650-biq0chyn	Torres, Juan M	Safety evaluation of a recombinant myxoma-RHDV virus inducing horizontal transmissible protection against myxomatosis and rabbit haemorrhagic disease	2000-09-15		.txt	text/plain	4589	226	45	title: Safety evaluation of a recombinant myxoma-RHDV virus inducing horizontal transmissible protection against myxomatosis and rabbit haemorrhagic disease Safety evaluation of a recombinant myxoma-RHDV virus inducing horizontal transmissible protection against myxomatosis and rabbit haemorrhagic disease In order to protect wild rabbits against both myxomatosis and RHD, we constructed a recombinant virus based on the naturally attenuated MV ®eld strain 6918 [24] , that expressed the RHDV VP60 protein [25] . Groups of eight wild rabbits (2 month old, weighing around 0.8 kg) free from MV and RHDV antibodies, were inoculated at the back by intradermic (i.d.) or subcutaneous (s.c.) route with dierent doses of the vaccine (10 4 , 10 5 , 10 6 pfu of 6918VP60-T2 recombinant virus). Treated rabbits were inoculated (by s.c or i.d. route) with 10 4 pfu of 6918VP60-T2 virus, and clinical signs due to virus infection were compared with those induced in control rabbits, which were vaccinated but not treated with prednisolone (Fig 2, Table 3 ).	./cache/cord-271650-biq0chyn.txt	./txt/cord-271650-biq0chyn.txt