id author title date pages extension mime words sentences flesch summary cache txt cord-272052-8vvpm4tx Hartmann, Katrin Clinical aspects of feline immunodeficiency and feline leukemia virus infection 2011-10-15 .txt text/plain 9582 444 35 In a survey study of 826 naturally FIV-infected cats examined at North American Veterinary Teaching Hospitals, the most common disease syndromes were stomatitis, neoplasia (especially lymphoma and cutaneous squamous cell carcinoma), ocular inflammation (uveitis and chorioretinitis), anemia and leukopenia, opportunistic infections, renal insufficiency, lower urinary tract disease, and endocrinopathies such as hyperthyroidism and diabetes mellitus (Levy, 2000a) . Causes of CD4 + cell loss include decreased production secondary to bone marrow or thymic infection, lysis of infected cells induced by FIV itself (cytopathic effects), destruction of virus-infected cells by the immune system, or death by apoptosis (cell death that follows receipt of a membrane signal initiating a series of programmed intracellular events) (Bishop et al., 1993; Ohno et al., 1993 Ohno et al., , 1994 Johnson et al., 1996; Guiot et al., 1997a,b; Mizuno et al., 1997; Mortola et al., 1998a,b; Piedimonte et al., 1999; Mizuno et al., 2001 Mizuno et al., , 2003b Tompkins et al., 2002) . ./cache/cord-272052-8vvpm4tx.txt ./txt/cord-272052-8vvpm4tx.txt