id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-273372-69rlh9or	Litterman, Nadia	Small molecules with antiviral activity against the Ebola virus	2015-02-09		.txt	text/plain	3257	157	48	In addition we propose that a collaborative database for sharing such published and novel information on small molecules is needed for the research community studying the Ebola virus. We have found that indeed there is much prior knowledge regarding small molecules that have been shown to be active against the Ebola virus in vitro or in animal models 10-13 , including a number of FDA-approved drugs 14-16 . Medicinal chemistry analysis of small molecules active against the Ebola virus We have recently described an expert's medicinal chemistry 26 analysis of the over 320 NIH probe compounds using public and commercial sources of chemical structures and the issues related to doing this type of analysis 27 . By organizing the data on small molecules tested against the Ebola virus similarly in a central database and using machine learning models based on public data may help identify additional compounds for testing.	./cache/cord-273372-69rlh9or.txt	./txt/cord-273372-69rlh9or.txt