id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-273708-2q64at3z	Annunziata, Giuseppe	May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence	2020-05-15		.txt	text/plain	3067	148	34	In this context, a great interest has been focused on resveratrol (RSV), whose antiviral mechanisms of actions are mainly attributable to its ability to inhibit the viral replication via (i) inhibition of immediate-early virus protein expression (i.e., ICP-4 and−27), (ii) inhibition of the NFκB signaling pathway, and (iii) activation of the AMPK/Sirt1 axis in the host cell (14) . The present mini-review aimed to report the few promising evidence regarding the potential anti-coronavirus activity of polyphenols, which may serve to drive the research toward the development of novel strategies to counteract the SARS-CoV2 pandemic. Studies available in the literature agree in establishing that the reduction of virus titer and the inhibition of nucleocapsid protein expression are their main general mechanisms of action at the base of this promising effect of polyphenols.	./cache/cord-273708-2q64at3z.txt	./txt/cord-273708-2q64at3z.txt