id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-276506-dj7dyo0x	Coria, M. F.	Protective effect of an inactivated avian coronavirus vaccine administered by aerosol	1973		.txt	text/plain	1796	116	51	Chickens administered 2 doses of the inactivated Connecticut strain (IBV-46) vaccine by aerosol at 3-week intervals had significant levels of virus-neutralizing antibodies and were resistant to infection by the Massachusetts strain (IBV-41) as determined by virus isolation attempts. Immunity to avian infectious bronchitis (AIB), a highly contagious viral infection of the respiratory tract of chickens has been studied using live and inactivated virus vaccirres (6) . However, more recent evidence shows that a BPL-inactivated AIB virus vaccine administered by an aerosol and concurrent subcutaneous inoculation induced significant levels of VN antibodies and afforded a good degree of protection against infection (4) . Immunization of the human respiratory tract with inactivated influenza A2 I-IongKong virus (13) and rhinovirus type 13 (ii), administered by an aerosol, indicates that a significant protective effect was observed when compared to individuals vaccinated by subcutaneous or intra-muscular routes. The immune response to BPL-inactivated AIB virus vaccines administered by an aerosol, as determined by PI~-NI's, virus isolation (VI) and respiratory signs are shm~a~ in Table 1 .	./cache/cord-276506-dj7dyo0x.txt	./txt/cord-276506-dj7dyo0x.txt