id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277392-s0bldxg9	Cann, Alan J.	Replication	2012-02-29		.txt	text/plain	7934	376	49	This simple step is the key to the entire experiment, because it effectively synchronizes the infection of the cells and allows the subsequent phases of replication in a population of individual cells and virus particles to be viewed as if they were a single interaction (in much the same way that molecular cloning of nucleic acids allows analysis of populations of nucleic acid molecules as single species). (At the time, it was generally believed that proteins, which consist of a much more complex mixture of more than 20 different amino acids, were the carriers of the genes and that DNA was probably a structural component of cells and viruses.) Together, these two experiments illustrate the essential processes of virus replication. n Fusion of the virus envelope (so this is only applicable to enveloped viruses) with the cell membrane, either directly at the cell surface or following endocytosis in a cytoplasmic vesicle (Figure 4.12) , which requires the presence of a specific fusion protein in the virus envelopedfor example, influenza hemagglutinin or retrovirus transmembrane (TM) glycoproteins.	./cache/cord-277392-s0bldxg9.txt	./txt/cord-277392-s0bldxg9.txt