id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-278479-vl296i1b	Samuel, Arthur S	Experimental infection of hamsters with avian paramyxovirus serotypes 1 to 9	2011-02-23		.txt	text/plain	6316	335	46	In this study, groups of hamsters were infected with a prototype strain of each APMV serotype by the intranasal route and monitored for virus replication, clinical symptoms, histopathology, and seroconversion. Our results showed that each of the APMV serotypes replicated in hamsters without causing adverse clinical signs of illness, although histopathologic evidence of disease was observed in some cases, and also induced high neutralizing antibody titers. Necropsies were performed immediately postmortem and the following tissue samples were collected for immunohistochemistry (IHC), histopathology, and virus isolation: brain, nasal turbinates, lung, spleen, kidney and small intestine. Deparaffinized sections of the virus-infected and uninfected control tissue (brain, lungs, nasal turbinates, small intestine, kidney, and spleen) were immunostained using polyclonal antisera against the N protein of the homologous APMV serotypes. In animals infected with any of the other APMV serotypes, virus-specific antigens were detected on 3 dpi in the lungs and nasal turbinates (Figure 3 ).	./cache/cord-278479-vl296i1b.txt	./txt/cord-278479-vl296i1b.txt