id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-278973-82n0d1dh	Li, Zhijie	Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats	2016-05-31		.txt	text/plain	3737	207	53	This study describes the isolation, molecular characterization and analysis of pathogenicity of MRV variant B/03 from wild short-nosed fruit bats. BALB/c mice experimentally infected with B/03 virus by intranasal inoculation developed severe respiratory distress with tissue damage and inflammation. MRV isolates were obtained from hosts with or without clinical signs of disease, and the virus can infect a broad range of mammals (Dermody et al., 2013) . In this study, we report the characterization of a novel MRV strain (called "B/03") isolated from healthy, wild shortnosed fruit bats in Guangdong province, China. In this study, one strain of MRV, B/03, was isolated by in vitro cell culture from thirty wild short-nosed fruit bat samples from Shaoguan city of China's Guangdong province. Based on sequence comparison and phylogenetic analysis, we conclude that the B/03 isolate is a novel type 1 bat orthoreovirus, and it might have originated from gene segment mixing during infection with more than one MRV strain in nature.	./cache/cord-278973-82n0d1dh.txt	./txt/cord-278973-82n0d1dh.txt