id author title date pages extension mime words sentences flesch summary cache txt cord-279557-hk77e3pp Drosten, Christian Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection 2013-06-17 .txt text/plain 4214 243 55 BACKGROUND: The Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus involved in cases and case clusters of severe acute respiratory infection in the Arabian Peninsula, Tunisia, Morocco, France, Italy, Germany, and the UK. [4] [5] [6] Here, we provide a full description of a fatal case of MERS-CoV infection imported to Munich, Germany, from Abu Dhabi, including a chronological profi le of virus concentrations in diverse body compartments. We subjected all available MERS-CoV genome sequences to phylogenetic analysis, including a correlation and regression analysis of known dates of virus isolation versus tree branch lengths (fi gure 3). Without quantitative laboratory data from well documented cases of MERS-CoV infection, most considerations had been made on the basis of an assumed analogy to severe acute respiratory syndrome (SARS). The recorded viral load profi le, with highest RNA concentrations in bronchoalveolar lavage and tracheobronchial aspirates, confi rms suggestions made in another report about the preferential use of lower-respiratory-tract samples for virus diagnostic tests. ./cache/cord-279557-hk77e3pp.txt ./txt/cord-279557-hk77e3pp.txt