id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286559-y8z0pwgn	Ding, Nai-Zheng	A permanent host shift of rabies virus from Chiroptera to Carnivora associated with recombination	2017-03-21		.txt	text/plain	4244	211	45	Bat virus host shifts have resulted in the emergence of several serious diseases in humans and animals, such as SARS 1 , Ebola 2 , and rabies 3 viruses. Interestingly, although evolutionary analyses have demonstrated that bat-to-carnivore host-shifting viruses accumulate few adaptive mutations 4, 6, 11 , in none of these examples did bat RABV establish permanent transmission cycles in the new host species 7 . The second permanent host shift appears to have occurred in North America, producing a lineage including two variants, raccoon rabies virus (RRV) and south-central skunk variant (SCSKV). Since bat RABVs are potentially able to infect carnivore species 6, 11, 14, 45 , we also propose that recombination may function as the third and fourth stages of establishment of a permanent host shift by significantly enhancing the adaptability of a bat virus in terrestrial mammals.	./cache/cord-286559-y8z0pwgn.txt	./txt/cord-286559-y8z0pwgn.txt