id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-287348-00yaxpkp	Martinez, Maria Jose Abad	Antiviral Activities of Polysaccharides from Natural Sources	2005-12-31		.txt	text/plain	7003	323	41	Although many compounds with potent antiviral activity in cell cultures and in experimental animals have been detected, at present only several molecules and a-interferon have been approved by the health authorities for therapy of viral infections in humans. Furthermore, several soluble derivatized dextrans with different percentages of carbomethyl, benzylamide and sulphonate/sulphate groups were also evaluated for possible inhibitory effects on HIV-1 infection, and from the results obtained, their use as anti-HIV therapeutic agents can be proposed [56] . Carrageenans and fucoidan are sulphated PS extracted from red seaweed and brown algae, which have shown potent inhibitory activity against different viruses including HIV. These compounds act as potent inhibitors of different enveloped viruses, including members of Herpesviridae, and their activity is linked to the anionic features of the molecule which hinder the attachment of viral particles to host cells.	./cache/cord-287348-00yaxpkp.txt	./txt/cord-287348-00yaxpkp.txt