id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-288348-b10e023s	Estes, Mary Kolb	Epidemic viral gastroenteritis	1979-06-30		.txt	text/plain	4523	232	39	Of the many viruses identified in stools, only two groups have met the criteria as definite etiologic agents of epidemic gastroenteritis in human subjects: rotaviruses and the small 27 nm agents [Norwalk-like agents) ( of investigations which began with an epidemic of gastroenteritis occurring in the newborn in the Baltimore-Washington area in the fall of 1941. Rotaviruses have been established as enteritis viruses by isolation and purification from stools of subjects suffering from gastroenteritis, and by induction of disease and seroconversion in both animals and volunteer subjects with purified preparations, Epidemiologic studies on the prevalence of rotavirus infections have shown these ubiquitous agents to be a major cause of gastroenteritis in children. Local immune factors, such as secretory immunoglobulin A or interferon, may therefore be important in protection against rotavirus infection, Alternatively, reinfection in the presence of circulating antibody could reflect the presence of multiple serotypes of virus [37] ; at least four agents in human subjects have been characterized to date [38-411.	./cache/cord-288348-b10e023s.txt	./txt/cord-288348-b10e023s.txt