id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290851-1e5e033r	Gerlier, Denis	Emerging zoonotic viruses: new lessons on receptor and entry mechanisms	2011-06-12		.txt	text/plain	2742	153	45	Here I review the receptors and mode of entry of three emerging zoonotic viruses, responsible for rare but deadly diseases, whose natural reservoir is the bat: severe acute respiratory syndrome coronavirus (SARS-CoV), Hendra (HeV), Nipah (NiV), Ebola (EboV), and Marburg (MarV) viruses. S mediates binding to the cellular receptor Angiotensin Converting Enzyme 2 (ACE2) [4 ] , and ensures the viral-cell membrane fusion that allows virus entry. The EboV (and MarV) entry process lasts for about 1 h [94, 95] and can be schematized as follows ( Figure 3) : Firstly, (i) EboV attaches to the cells via the GP1/GP2 interaction with DC-SIGN/R and/or LECStin and is (ii) immediately internalized by constitutive and/or virus-contact-induced macropinocytosis. Cell adhesion promotes ebola virus envelope glycoprotein-mediated binding and infection	./cache/cord-290851-1e5e033r.txt	./txt/cord-290851-1e5e033r.txt