id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-292353-z86rjwle	Hussein, Islam T.M.	Recent Advances in Hantavirus Molecular Biology and Disease	2011-04-01		.txt	text/plain	13579	708	47	Hantaviruses pose a serious threat to human health because their infection causes two highly fatal diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The sequences at both the 3 0 and 5 0 termini of each RNA segment are complementary forming ''panhandle'' structures that are specifically recognized by the N protein and were shown to be important for viral transcription and replication. Further studies revealed that cellular 5 0capped mRNA oligoribonucleotides are rescued by N in virus-infected cells and stored in P-bodies for the later use as primers by the viral RdRp during transcription initiation . The UTRs are encapsidated by nucleocapsid protein and associate with RdRp both in the host cells and in the virion, and only these nucleocapsids are believed to be functional templates for mRNA synthesis and RNA replication by the viral RdRp. c.	./cache/cord-292353-z86rjwle.txt	./txt/cord-292353-z86rjwle.txt