id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294812-nnlzwaf1	Desforges, Marc	Neuroinvasive and Neurotropic Human Respiratory Coronaviruses: Potential Neurovirulent Agents in Humans	2014-03-12		.txt	text/plain	7096	318	36	However, in some circumstances, viruses can avoid the immune response and cause more severe respiratory diseases [1] or even spread to other tissues, including the central nervous system (CNS), where they could induce other types of pathologies [7] . Coronaviruses, a family of enveloped positive-stranded RNA viruses with a characteristic crown-shaped appearance, are widespread in nature and can infect several different species [44] , in which they cause mainly respiratory and enteric pathologies, with neurotropic and neuroinvasive properties in various hosts including humans, cats, pigs, rodents, and fowl [45] [46] [47] [48] . Furthermore, we have shown that these viruses are able to establish a persistent infection in human cells representative of the CNS [64, 65] and that HCoV-OC43 RNA could be detected for at least a year in the CNS of infected mice that survived the virus-induced acute encephalitis [71] .	./cache/cord-294812-nnlzwaf1.txt	./txt/cord-294812-nnlzwaf1.txt