id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-299549-bjqwwzam	Zhang, Lei	Against Ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis	2015-01-01		.txt	text/plain	3644	191	47	When the viral infection proceeds to the terminal stage, the key factor would be applying a non-specific immune modulation approach to suppress the cytokine storm that causes multiple organ failure, in an attempt to open a time window for the host's immune system to recover. In most patients, Ebola viral burden elevates by time and triggers an extremely strong immune attack-a phenomenon called 'cytokine storm' (Sullivan et al., 2003) , during which monocytes and/or macrophages produce a massive amount of pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α) and interleukins (ILs), and The virus burden, inflammatory response, and specific antibodies are the main contributors to different outcomes: mortality, survival, or symptomless infection (Fig. 2) , suggesting that the appropriate intervention strategy in each stage would accordingly be able to control the Ebola virus. Nonetheless, this phenomenon does give clues to the treatment against Ebola virus disease (EVD)-early activated innate immune responses may prevent the viral infection.	./cache/cord-299549-bjqwwzam.txt	./txt/cord-299549-bjqwwzam.txt