id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-306424-gf0bglm0	Scutigliani, Enzo Maxim	Interaction of the innate immune system with positive-strand RNA virus replication organelles	2017-06-27		.txt	text/plain	8320	382	36	Thus, these data indicate that MAMs are critical locations for antiviral signaling and have an important role in expression of type I and III IFNs. Moreover, increasing evidence suggests that at least some +RNA viruses in fact occupy or hijack MAM-membranes during infection, as MAMs of HCV-infected cells were found to contain proteins involved in virus assembly and fully assembled virions [111] . At last, based on recent studies that demonstrated how IFN-g inducible GTPases are capable of disrupting PVs, we discussed the possibility of a general function of IFN-inducible GTPases in the targeting of viral ROs. In summary, upon infection, +RNA viruses hamper IFN and ISG induction at multiple levels to decelerate antiviral innate immune signaling. Antiviral innate immune response interferes with the formation of replication-associated membrane structures induced by a +RNA virus	./cache/cord-306424-gf0bglm0.txt	./txt/cord-306424-gf0bglm0.txt