id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310870-w8wu8vno	Shorten, Robert J.	The risk of transmission of a viral haemorrhagic fever infection in a United Kingdom laboratory	2017-05-18		.txt	text/plain	1636	97	45	[9] [10] [11] [12] In addition, over 9,000 cases of Crimean Congo Haemorrhagic Fever (CCHF) were reported in Turkey between 2002 and 2014, with an estimated minimum 180,000 blood samples processed in routine laboratories with no additional precautions. Although it is reassuring that large numbers of samples from patients with CCHF infection have been processed safely in routine laboratories in Turkey, it should be noted that this bunyavirus is rarely transmitted person to person, so the parallels between this and other VHF viruses need to be carefully considered. Manufacturers must validate their decontamination method against appropriate surrogate model enveloped viruses. Viral inactivation validation studies have successfully used surrogate model viruses with properties similar to wildtype viruses to provide evidence for the safety of human blood plasma products for over a decade. Once assessed by appropriately designed viral inactivation validation studies on relevant surrogate model enveloped viruses, the decontamination process has been shown to be effective against all known and future emerging enveloped viruses, which includes Ebola, CCHF, Lassa fever, and Marburg virus.	./cache/cord-310870-w8wu8vno.txt	./txt/cord-310870-w8wu8vno.txt