id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317851-lj07947c	Elena, S F	Experimental evolution of plant RNA viruses	2008-02-06		.txt	text/plain	4184	191	42	In this review, we will focus on recent studies that used plant viruses to address evolutionary questions of general interest, such as the rate and fitness effects of deleterious mutations and the role of neutrality as a source of mutational robustness, the evolution of generalist viruses, or the effect of vertical versus horizontal transmission on virulence. Despite mutation rate is still high compared to that of DNA-based microorganisms, a classic field observation is that natural plant virus populations generally exhibit limited genetic variation (García-Arenal et al., 2001) , which may imply either that purifying selection may be strong or that genome replication occurs mainly by Luria's stamping machine model (Luria, 1951) rather than exponentially (French and Stenger, 2003) , the two hypotheses being nonexclusive.	./cache/cord-317851-lj07947c.txt	./txt/cord-317851-lj07947c.txt