id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325750-x7jpsnxg	Mokili, John L	Metagenomics and future perspectives in virus discovery	2012-01-20		.txt	text/plain	8742	463	40	In this article, we review virus discovery techniques with a focus on metagenomic approaches that employ high-throughput sequencing technologies to characterize novel viruses. This method lacks sufficient sensitivity to detect viruses when the viral burden is low or when the DNA sequence of the suspected etiological agent is not clearly distinguishable from the control sample [31] . The following items should be included in any report on viral metagenomic studies: firstly, the sequencing platform and its version number; secondly, raw sequence data accession numbers in a public database; thirdly, details about the bioinformatic analysis, including the homology search tool and the database being used to assign the taxonomy, and their versions; fourthly, a list of known and previously unknown viruses found, clearly showing if the 'novel' viruses are new strains of a previously described species or completely different viruses; and fifthly, causality evidence if any.	./cache/cord-325750-x7jpsnxg.txt	./txt/cord-325750-x7jpsnxg.txt