id author title date pages extension mime words sentences flesch summary cache txt cord-332046-ihc031ly Li, Yan‐Chao Neurotropic virus tracing suggests a membranous‐coating‐mediated mechanism for transsynaptic communication 2013-01-01 .txt text/plain 4865 236 47 This study has systematically examined the assembly and dissemination of HEV 67N in the primary motor cortex of infected rats and provides additional evidence indicating that mem-branous-coating-mediated endo-/exocytosis can be used by HEV for its transsynaptic transfer. Consistent with the results in the previous experiments, the present study showed that at day 4 p.i. HEV-positive cells were observed in only a certain population of neurons with different sizes in layer V of the primary motor cortex (Fig. 1A,B) . Extracellular virions were not enclosed by any vesicular structures, whereas vesicle-enclosed virus particles were otherwise observed in the axonal terminals touching on the infected neurons, so it seemed that the virions within the synapses had acquired new vesicular membrane after entry. D shows a virion within a coated vesicle (arrow; see also the inset for details) in the axon terminal adjacent to an infected pyramidal cell. ./cache/cord-332046-ihc031ly.txt ./txt/cord-332046-ihc031ly.txt