id author title date pages extension mime words sentences flesch summary cache txt cord-338081-ggw5l1qm Gorbalenya, Alexander E. Phylogeny of Viruses 2017-06-26 .txt text/plain 3638 154 41 For inferring phylogeny, the differences between aligned sequences of genomes and proteins are quantified and depicted in the form of a tree, in which contemporary species and their intermediate and common ancestors occupy, respectively, the terminal nodes, internal nodes, and the root. Bayesian methods have the highest computational cost due to their sampling approach and thus show the lowest speed, while realization of the similarly advanced ML algorithm may be largely comparable in speed to distance methods, allowing for the phylogenetic analysis of very large data sets like genome-wide tree reconstructions of cellular organisms or thousands of viruses. In the case of SARS-CoV, poor sampling of the coronavirus diversity in the lineage at the time, some uncertainty over the relationship between phylogeny and taxonomy of coronaviruses, and the complexity of phylogenetic analysis of a virus data set including isolated distant lineages led to considerable controversy over the exact evolutionary position of SARS-CoV among coronaviruses. ./cache/cord-338081-ggw5l1qm.txt ./txt/cord-338081-ggw5l1qm.txt