id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-340042-intxyu46	Chaudhry, Sundas Nasir	New insight on possible vaccine development against SARS-CoV-2	2020-09-11		.txt	text/plain	5457	260	43	In December 2019, a novel virus, namely COVID-19, caused by SARS-CoV-2, developed from Wuhan, Hubei territory of China, which used its viral spike glycoprotein receptor-binding domain (RBD) for the entrance into a host cell by binding with ACE-2 receptor and cause acute respiratory distress syndrome (ARDS). Different subunits of spike proteins like the S1 and S2 subunits, and the receptor-binding domain (RBD) are the critical elements for the formation of a vaccine against the newly emerged virus that helped in producing T cell responses and protective immunity against SARS-CoV-2 [29] . The recombinant protein is known as one of the emerging fields for the development of a vaccine against viruses due to several properties including tight binding to specific ACE-2 receptor, provoke immune protection against viral infections, increase antibody-dependent viral entry, and promote antigenicity against virus like SARS-CoV [52] .	./cache/cord-340042-intxyu46.txt	./txt/cord-340042-intxyu46.txt