id author title date pages extension mime words sentences flesch summary cache txt cord-340194-ibli36rq To, Kelvin K.W. Ebola virus disease: a highly fatal infectious disease reemerging in West Africa 2014-11-29 .txt text/plain 8870 485 51 Ebolavirus has been known to cause outbreaks of severe hemorrhagic fever with high fatality in Africa since 1976 [1] . Zaire and Sudan ebolavirus are responsible for most outbreaks, and these species are associated with highest case-fatality rates, ranging from 44e100% and 41e69%, respectively. In addition to clinically apparent EVD outbreaks, seroepidemiology studies showed that there is a high prevalence seropositive individuals, suggesting that asymptomatic or mild infection can occur [15] . The only human case of ebolavirus infection in West Africa before the 2014 outbreak occurred 20 years ago. During the 1976 EVD outbreak, the index case had transmitted the virus to healthcare workers and hospitalized patients with at least 15 generations of person-to-person transmission [29] . Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels ./cache/cord-340194-ibli36rq.txt ./txt/cord-340194-ibli36rq.txt