id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341101-5yvjbr5q	Hashem, Anwar M.	Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review	2020-05-06		.txt	text/plain	4823	275	43	While approved specific antiviral drugs against SARS-CoV-2 are still lacking, a large number of existing drugs are being explored as a possible treatment for COVID-19 infected patients. In general, studies showed no significant effect of CQ on CoVs including SARS-CoV and feline infectious peritonitis virus (FIPV) replication or clinical scores in mice and cats, respectively [105, 110] . There are very limited published clinical trials that studied the possible antiviral effect of CQ or HCQ in CoV and non-CoV infected patients (Table 5 ). Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro	./cache/cord-341101-5yvjbr5q.txt	./txt/cord-341101-5yvjbr5q.txt