id author title date pages extension mime words sentences flesch summary cache txt cord-344970-ud1lhkyi Fecchi, Katia Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets 2020-08-11 .txt text/plain 5433 276 43 Lipid rafts are specialized plasma membrane microdomains involved in important processes of the virus infections and of the host target cells (Rosenberger et al., 2000) . This minireview reports on the available knowledge about the interplay between coronaviruses, including the SARS-CoV-2, with lipid rafts and autophagic pathways, in order to focus the attention to novel potential targets to inhibit coronavirus infections. As outlined in this review, lipid rafts and autophagic pathways play a pivotal role in coronavirus infection, being critical for viral entry and replication, as well as for viral release from the host cells. In fact, different drugs described as inhibitors or inducers of the autophagy that control host cell pathways process involved in coronavirus infection, have sparked interest for their potential antiviral activity (Shakya et al., 2018; Liu et al., 2019; Xu et al., 2020; Yang et al., 2020 ; Table 1 ). ./cache/cord-344970-ud1lhkyi.txt ./txt/cord-344970-ud1lhkyi.txt