id author title date pages extension mime words sentences flesch summary cache txt cord-346853-0c1qdjb5 Holmes, E. C. The Evolutionary Genetics of Viral Emergence 2007 .txt text/plain 6123 261 45 Despite the wealth of data describing the ecological factors that underpin viral emergence, little is known about the evolutionary processes that allow viruses to jump species barriers and establish productive infections in new hosts. We also emphasize the current lack of convincing data as to whether viral emergence requires adaptation to the new host species during the early stages of infection, or whether it is largely a chance process involving the transmission of a viral strain with the necessary genetic characteristics. For example, one model of viral emergence posits that adaptation to a new host species during the early period of an epidemic is of fundamental importance, because this raises the basic reproductive rate of the virus, R 0 , to greater than 1, so that sustained transmission networks can be established (Anita et al. ./cache/cord-346853-0c1qdjb5.txt ./txt/cord-346853-0c1qdjb5.txt