id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-348163-9q1rt8i7	Hussein, Hosni A. M.	Beyond RGD: virus interactions with integrins	2015-09-01		.txt	text/plain	5945	301	36	Integrins are a family of receptor molecules that serve as entry receptors for a variety of different viruses, including foot-and-mouth disease virus (FMDV) [97] , Kaposi's sarcoma-associated herpesvirus (KSHV) [5], herpes simplex virus-2 (HSV-2) [31], adenovirus [168] , human papillomavirus-16 (HPV-16) [3] , reovirus [40] , and others. On the other hand, interactions of viruses with cellular integrins induce conformational changes in the viral surface proteins, helping to expose the essential domains required for virus entry into a host cell [107] . Similarly, several human herpesviruses, including HSV [147] , KSHV [4], and CMV [93] , make their initial contact with cells by binding to cellsurface HSPGs. In general, binding of viruses to carbohydrate moieties on the surface of cells is the key step that induces conformational changes in the viral structure that are critical for interactions with entry-promoting receptors such as integrins.	./cache/cord-348163-9q1rt8i7.txt	./txt/cord-348163-9q1rt8i7.txt