id author title date pages extension mime words sentences flesch summary cache txt cord-350747-5t5xthk6 Gmyl, A. P. Diverse Mechanisms of RNA Recombination 2005 .txt text/plain 8187 463 41 It was believed until recently that the only possible mechanism of RNA recombination is replicative template switching, with synthesis of a complementary strand starting on one viral RNA molecule and being completed on another. An illustrative example of deletions is provided by defective interfering (DI) genomes, which accumulate in a virus population upon high-multiplicity infections and lack a fragment of the sequence coding for viral proteins [5] [6] [7] . A special role in the variation of RNA viruses is played by recombination, the generation of new genomes from two or more parental RNAs. Recombination between viral RNA molecules was observed for the first time as early as in the 1960s in the poliovirus [14, 15] . In other words, it is possible to assume that some of the mechanisms of nonreplicative RNA recombination play an important role in the evolution of not only viral, but also cell genomes [51, 90] . ./cache/cord-350747-5t5xthk6.txt ./txt/cord-350747-5t5xthk6.txt