id author title date pages extension mime words sentences flesch summary cache txt cord-350948-oog6m4h3 Leclercq, Loïc How to improve the chemical disinfection of contaminated surfaces by viruses, bacteria and fungus? 2020-09-17 .txt text/plain 4571 256 51 The disinfectants, based on equimolar mixtures of didecyldimethylammonium chloride ([DiC(10)][Cl]), dodecyloctaglycol (C(12)E(8)), and cyclodextrin (CD), show synergistic effects against enveloped viruses (RSV, HSV-1, VACV) and fungi (C. In this context, the didecyldimethylammonium chloride ([DiC 10 ] [Cl] ), one of the most widely used quaternary ammonium compounds in healthcare systems to prevent and control viral infections due to its ability to disorganize and to disrupt the envelopes of viruses (Leclercq et al., 2010) , is associated with detergents, such as dodecyloctaglycol (C 12 E 8 ), making the detergent-disinfectant combination ideal for general sanitation purposes (Rauwel et al., 2012) . As, some ethoxylated surfactants (e.g. Triton X-100, Nonoxynol-9 or Brij-97) have been shown to exhibit a virucidal activity due to their ability to solubilize the viral envelope of Epstein-Barr or herpes simplex viruses (Qualtiere and Pearson, 1979; Asculai et al., 1978) , and, as, CDs "are able to participate in the attack of viruses, and specifically SARS-CoV-2, in a large range of different ways" (Garrido et al., 2020) , we have investigated [DiC 10 ][Cl]/C 12 E 8 /CD ternary systems to obtain synergistic effects against enveloped viruses such as RSV instead of hazardous SARS-CoV-2. ./cache/cord-350948-oog6m4h3.txt ./txt/cord-350948-oog6m4h3.txt