id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-355771-pxkkd3s1	Olagnier, David	Oncolytic Viral Immunotherapy in the Time of COVID-19	2020-11-04		.txt	text/plain	1793	81	38	The 2020 global pandemic of Covid-19 has refocused the entire scientific community towards understanding the SARS coronavirus-2 (SARS-CoV-2) and developing urgently needed therapies and vaccines to halt the spread of this newly emerging virus. In this special issue of Cytokines and Growth Factor Reviews -Oncolytic Viral Immunotherapy 2020, international experts discuss the innovative approaches developed for OV-based immunotherapies. Interferons (IFNs) are the most potent anti-viral cytokines induced by virus-infected cells and can reduce the efficacy of OVs. However, many types of cancer cells have been shown to be compromised in terms of generating a potent IFN antiviral state, thus making these tumours a particularly sensitive niche population for oncolytic virus replication. Four reviews in this issue describe our current understanding of the factors that can contribute to a successful super-spreading oncolytic and immune stimulating event within tumours.	./cache/cord-355771-pxkkd3s1.txt	./txt/cord-355771-pxkkd3s1.txt