id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-276942-dk1rk908	Ebadi, Maryam	Perspective: improving vitamin D status in the management of COVID-19	2020-05-12		.txt	text/plain	2218	108	39	In vitro culture of human fetal and adult alveolar type-II cells with 1,25-dihydroxyvitamin D increased VDR and the expression of surfactantassociated protein B, a lipid-associated protein of the pulmonary surfactant [23] , indicating the potential of vitamin D to reduce surface tension in COVID-19. In line with our objective to improve vitamin D status and its associated outcomes in patients with COVID-19, studies have shown treatment with high dose of 250,000-500,000 IU vitamin D to be safe in mechanically ventilated, critically ill patients and was associated with decreased hospital length of stay, improved ability of the blood to carry oxygen and increased hemoglobin levels [24, 25] . High prevalence of vitamin D deficiency in elderly, smokers, patients with chronic diseases, and excess uptake by adipose tissue in obesity make investigations of its role as a therapeutic agent in COVID-19 conceivable.	./cache/cord-276942-dk1rk908.txt	./txt/cord-276942-dk1rk908.txt