id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-321817-z9oj9nmv	Cereda, Emanuele	Vitamin D supplementation and outcome in COVID-19 patients from the outbreak area of Lombardy, Italy	2020-11-11		.txt	text/plain	1483	79	42	• The involvement of vitamin in the pathophysiology of COVID-19 is still not clear; • Some studies support a link between vitamin D deficiency and worse COVID-19 outcome; • Vitamin D may also enhance macrophages activation and aberrant immune response; • In our study vitamin D supplementation was associated with a trend to higher mortality; • Supplementation trials are crucial to clarify the role of vitamin D in COVID-19. The observation of lower mortality rates at lower degrees of latitude, along with other preliminary reports on the association between serum levels of 25OHD and the risk of having the disease or a critical outcome, have suggested that vitamin D could modulate the risk and mitigate the severity of COVID-19 [1, 2, 5] . Therefore, we aimed to evaluate whether vitamin 25OHD supplementation, which may be a better surrogate of real 25OHD status, is associated with prognosis in COVID-19 patients from the Italian outbreak area of Lombardy. Further studies are needed to clarify the role of vitamin D supplementation and status in modulating the severity of COVID-19, as well as its prevention.	./cache/cord-321817-z9oj9nmv.txt	./txt/cord-321817-z9oj9nmv.txt