id author title date pages extension mime words sentences flesch summary cache txt cord-330834-zqm4egei Drall, Kelsea M. Vitamin D supplementation in pregnancy and early infancy in relation to gut microbiota composition and C. difficile colonization: implications for viral respiratory infections 2020-08-11 .txt text/plain 4509 228 35 Since little is known about the impact of this supplementation on infant gut microbiota, we undertook a study to determine the association between maternal and infant vitamin D supplementation, infant gut microbiota composition and Clostridioides difficile colonization in 1,157 mother-infant pairs of the CHILD (Canadian Healthy Infant Longitudinal Development) Cohort Study over 2009–2012. 2, 20 The primary objective of this study was to determine the association between maternal perinatal and infant vitamin D supplementation, and infant gut microbiota composition at 3 months of age, including C. These null associations were unchanged following adjustment for birth mode, maternal milk consumption, household pets, study center and infant age at sample collection ( Figure 1a , Table S1 ). 46 Ultimately, this study found evidence of an association between maternal vitamin D supplementation with the gut microbiota composition of all study infants, notably a lower abundance of Megamonas, with its potential implications for host defense against viral respiratory infections. ./cache/cord-330834-zqm4egei.txt ./txt/cord-330834-zqm4egei.txt