id author title date pages extension mime words sentences flesch summary cache txt cord-004053-nmt221tu Goh, Gerard Kian-Meng Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity 2019-11-06 .txt text/plain 6456 326 60 Percentages of intrinsic disorder (PIDs) of M and C shell proteins from Zika virus (ZIKV) strains with UniProt accession. According to our research on other viruses, the capsid association with virulence involves a mechanism of protein promiscuity, whereby intrinsic disorder allows the capsid protein (the C protein, in the case of flaviviruses) to bind to a greater number of proteins, thereby allowing the virus to multiply more rapidly before the host immune system can take action [2, 14, 51] . It is therefore likely that the different PIDs of C proteins from the various ZIKV strains and lineages are the result of the types of primates that the peculiar ZIKV strain primarily infects and its ability to fine-tune its C disorder to meet the optimal viral load necessary for more efficient transmission of the virus in a given host, as seen in the case of other viruses and other flaviviruses [2, 14, 25, 39, 49, 50] . ./cache/cord-004053-nmt221tu.txt ./txt/cord-004053-nmt221tu.txt